A new TaqI allele at DXS52 frequent in Algeria

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TaqI RFLP at D21S137.

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A third TaqI allele is detected by the probe pTD3-21 (D15S10) in southern African chromosomes.

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TaqI identifies a four allele DNA polymorphism of the human endothelin-1 gene (EDN1).

Chromosomal Localization: The EDN1 gene has been assigned by somatic cell hybrid analysis to human chromosome 6 (1). We have obtained additional information on the localization of this gene through genetic mapping evidence for linkage was given to loci F13A and D6S7 (which are located at the tip of chromosome 6) at recombination fractions = 0.07, and to various HLA markers at recombination frac...

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BACKGROUND Mounting evidence suggests the involvement of the dopamine system in the pathophysiology of obsessive-compulsive disorder. METHOD The relationship of the dopamine D(2) receptor (DRD2) TaqI A, and catechol-O-methyl-transferase (COMT) NlaIII High/Low activity polymorphism to obsessive-compulsive disorder (OCD) was examined in a sample of 150 patients and 150 controls. RESULTS OCD p...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 1989

ISSN: 0305-1048,1362-4962

DOI: 10.1093/nar/17.3.1276